Endocrine Abstracts

Transformation of a micro-prolactinoma to a macro-prolactinoma during pregnancy is rare. During treatment of micro-prolactinoma it is conventional to stop dopamine agonist treatment prior to or at conception and only re-image the pituitary if the patient presents with symptoms or signs of pituitary enlargement. We present two cases of micro-prolactinoma transforming to macro-prolactinoma during pregnancy. Neither case presented with symptoms or signs of pituitary enlargement. ...

Aim: The aim of our study was to explore the possibility of using a district-wide laboratory database as a governance tool to ensure the optimum management of patients with biochemical hyperthyroidism.Patients and methods: A complete list of patients on whom TFT were requested over a 3-month period was obtained and patients with unequivocal hyperthyroidism were identified. General practitioners (GP) of patients not referred to the specialist endocrine te...

Case report;A 42-year-old male presented with headache, coarserning of facial features, enlargement of body parts of 2 years duration. There was no visual disturbance. His height was 168cms, wt 71kg and BMI of 25Kg/ per met square.He was normotensive .Biochemical and hormonal profile revealed he was euglycemic, euthyroid, serum cortisol(am)280nmo/lit(normal 450-700nmo/lit) non suprresible GH values of 46 ng/ml with 75gms of oral glucose (normal< 1 ng ...

IntroductionHypercalcemia is a recognised feature of parathyroid and neoplastic disorders and similarly erythrocytosis is recognised in some benign and malignant neoplasm.Case reportA 71-year-old man presented to the admissions unit with an episode of collapse. No significant neurological or cardiovascular cause was identified. The results of his routine investigation revealed haemoglobin of 19.7g/dl and a ...

The 1997 working party recommendations for the management of patients with pituitary tumours suggest formal assessment by an endocrinologist prior to tertiary referral. We have examined the extent of endocrine assessment in such patients performed both by endocrine and non-endocrine specialists in a large district general hospital. Using ICD 9 & 10 coding records on patients discharged between 1993 and 2000, we identified 60 patients with pituitary pathology. Of these, 1...

AbstractThe diagnosis of osteomyelitis in diabetes mellitus remains a challenge. This study was conducted to evaluate the infection scintigraphy with instantly prepared single vial kit, radio-labelled ciprofloxacin (Diagnobact TM), as a mean to detect bone infection; in comparison with bacterial culture as gold standard. Written consent was taken from all patients including approval from institute ethics committee. Twenty-five patients with diabetic foot...

Neuroendocrine tumours are uncommon and often present difficult therapeutic challenges. They may be composed of different cell types and are often multihormonal. We present the case of a 75 year-old man diagnosed to have a glucagonoma in 1995. He was deemed unfit for curative surgery and was managed medically including insulin therapy for control of hyperglycaemia. Over the next 7 years the patient became progressive more symptomatic due to increase in tumour size and hepatic ...